Our goal is to publish findings that contribute to a deeper understanding of biological systems.

6 Featured Papers.

1: Wooten et al., Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers.
PLoS Comput Biol. 2019 31;15(10):e1007343. doi: 10.1371/journal.pcbi.1007343.

2: Rudin et al., Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.
Nat Rev Cancer. 2019; 19(5):289-297. doi: 10.1038/s41568-019-0133-9.

3: Meyer et al., Quantifying Drug Combination Synergy along Potency and Efficacy Axes.
Cell Syst. 2019; 8(2):97-108.e16. doi: 10.1016/j.cels.2019.01.003.

4: Paudel et al., A Nonquiescent “Idling” Population State in Drug-Treated, BRAF-Mutated Melanoma.
Biophys J. 2018; 114(6):1499-1511. doi: 10.1016/j.bpj.2018.01.016.

5: Udyavar et al., Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity.
Cancer Res. 2017; 77(5):1063-1074. doi: 10.1158/0008-5472.CAN-16-1467.

6: Harris et al., An unbiased metric of antiproliferative drug effect in vitro.
Nat Methods. 2016; 13(6):497-500. doi: 10.1038/nmeth.3852.